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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NFIC All Species: 16.06
Human Site: S386 Identified Species: 44.17
UniProt: P08651 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08651 NP_005588.2 508 55675 S386 S I L P Q T A S T Y F P H T A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001117899 1094 117090 S770 S I L P Q T A S T Y F P H T A
Dog Lupus familis XP_542179 569 62116 S449 S I L P Q T A S T Y F P H T A
Cat Felis silvestris
Mouse Mus musculus P70255 439 48750 S323 D I E G G I S S P V K K T E M
Rat Rattus norvegicus P09414 509 55958 F383 I Q Q P G P Y F S H P A I R Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507360 560 62601 S378 A I L P P A P S S Y F S H P T
Chicken Gallus gallus P17926 439 49214 P323 D M E G G I S P N V K T E M D
Frog Xenopus laevis NP_001089972 501 55469 S379 S S L L P Q A S T Y F P H T A
Zebra Danio Brachydanio rerio XP_001921162 553 61079 H409 T A S T Y F P H T A I R Y P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 46 86.9 N.A. 82.4 65.2 N.A. 54.4 79.3 81.8 75.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 46.2 87.8 N.A. 84.4 75.4 N.A. 65 82.6 90.1 83.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 13.3 6.6 N.A. 46.6 0 73.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 20 20 N.A. 60 13.3 73.3 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 12 0 0 0 12 45 0 0 12 0 12 0 0 45 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 23 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % D
% Glu: 0 0 23 0 0 0 0 0 0 0 0 0 12 12 0 % E
% Phe: 0 0 0 0 0 12 0 12 0 0 56 0 0 0 0 % F
% Gly: 0 0 0 23 34 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 12 0 12 0 0 56 0 0 % H
% Ile: 12 56 0 0 0 23 0 0 0 0 12 0 12 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 23 12 0 0 0 % K
% Leu: 0 0 56 12 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 12 0 0 0 0 0 0 0 0 0 0 0 12 12 % M
% Asn: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % N
% Pro: 0 0 0 56 23 12 23 12 12 0 12 45 0 23 12 % P
% Gln: 0 12 12 0 34 12 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 12 0 12 0 % R
% Ser: 45 12 12 0 0 0 23 67 23 0 0 12 0 0 0 % S
% Thr: 12 0 0 12 0 34 0 0 56 0 0 12 12 45 12 % T
% Val: 0 0 0 0 0 0 0 0 0 23 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 12 0 12 0 0 56 0 0 12 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _